Product Overview:
Mustela Baby 1-2-3 Vitamin Barrier Cream is a scientifically formulated, dermatologically tested diaper rash ointment designed to prevent, relieve, and repair skin discomfort from the very first use. Developed with pediatricians and dermatologists, this barrier cream delivers a triple-action defense system against diaper rash and skin irritation, while being gentle enough for daily use from birth onward — even on newborns discharged from neonatal care.
Its formula contains 98% naturally derived ingredients, including vitamin-rich emollients, soothing plant extracts, and non-occlusive protective agents that support the skin’s microbiome and natural barrier function. Free from fragrances, preservatives, and known allergens, this cream is ideal for sensitive, fragile, and irritation-prone infant skin.
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Key Benefits: The 1-2-3 Triple-Action Formula
1. PREVENTS Irritation and Redness
Forms a breathable yet protective barrier between the diaper and the baby’s delicate skin.
Reinforces the skin’s natural defenses, minimizing the risk of contact dermatitis caused by prolonged exposure to moisture, friction, and digestive enzymes (lipase/protease in feces and urine).
2. RELIEVES Discomfort from the First Application
Quickly calms inflammation and soothes discomfort with a combination of panthenol (pro-vitamin B5) and vitamin F, known for their skin conditioning and anti-inflammatory properties.
Reduces erythema, itching, and discomfort associated with diaper rash and irritation.
3. REPAIRS the Skin Barrier Long-Term
Supports epidermal regeneration with vitamin B5 and vitamin E, while avocado perseose®, a patented biomimetic active ingredient, helps restore the skin’s moisture barrier and cellular integrity.
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Key Active Ingredients and Their Functions
Zinc Oxide (10%) – Provides a non-occlusive, breathable barrier that protects against diaper friction and moisture while offering mild antiseptic and astringent benefits.
Avocado Perseose® – A patented natural sugar extracted from avocado that protects the skin barrier, preserves cellular resources, and strengthens skin defenses.
Panthenol (Vitamin B5) – Promotes skin repair, reduces inflammation, and enhances hydration.
Vitamin F (Linoleic Acid Complex) – Strengthens the lipid layer and supports regeneration of the skin’s protective film.
Vitamin E (Tocopherol) – Offers antioxidant protection and supports healthy skin renewal.
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Formulation and Sensory Profile
Texture: Creamy, non-greasy, and easy to apply without tugging at delicate skin.
Finish: Semi-occlusive and breathable; leaves a thin, white protective layer that stays in place between diaper changes.
Fragrance-Free & Preservative-Free: Minimizes the risk of allergic reactions and skin sensitization, even with frequent use.
Dermatologist & Pediatrician Tested: Hypoallergenic and suitable for use on newborns, including NICU-discharged babies.
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Clinical Efficacy
Clinically Proven Results:
80% reduction in diaper rash symptoms within the first 3 days of use
90% of pediatricians recommend for prevention and daily protection
Long-term use shown to decrease the frequency and severity of diaper rash episodes
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How to Use:
Apply a thick layer to clean, dry skin at each diaper change — especially before prolonged sleep or after episodes of loose stools.
Safe for use at every diaper change from birth onward.
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Additional Information:
Size: 100ml tube (also available in 50ml and 150ml sizes)
Free From: Parabens, phthalates, phenoxyethanol, alcohol, fragrances, dyes
Environmentally Conscious: Biodegradable formula and recyclable packaging; developed under eco-design principles.
About this item
Effective Diaper Rash Relief: Mustela Baby 123 Vitamin Barrier Cream is specially formulated to provide effective relief and prevention of diaper rash.
Triple Action: This cream offers triple action protection by creating a protective barrier on your baby's skin, soothing discomfort, and supporting skin recovery.
Enriched with Vitamins: Infused with vitamins B5 and F, it helps to reinforce the skin barrier and keep your baby's skin healthy.
Convenient Size: The 100ml size is perfect for on-the-go use and fits easily into your diaper bag.
Trusted Made In Frnace Brand: Mustela has been a trusted brand for baby skincare for over 70 years, recommended by pediatricians worldwide.
Diaper Rash Relief Bundle: Get three 100ml tubes of Mustela Baby 123 Vitamin Barrier Cream for the price of two, ensuring you have ample supply for your baby's diaper rash care.
Vitamin Barrier / Diaper Rash Cream 1 2 3
Our best-selling diaper rash cream is formulated with 98% of natural ingredients, including our patented Avocado Perseose. Combined with Zinc Oxide, this fragrance-free cream is hypoallergenic and safe to use from birth on.
Fragrance-free
Paraben-free
Phthalate-free
Phenoxyethanol-free
For Diaper Change
Mustela’s Diaper Rash Cream is the ideal 3-in-1 solution that prevents diaper rash, relieves irritation and restores delicate skin at every diaper change. Easy to apply and wipe off, it is the perfect addition to your diaper-change regimen
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